Mesopotamia (from the Greek, meaning 'between two rivers’) was an ancient region in the eastern Mediterranean bounded in the northeast by the Zagros Mountains and in the southeast by the Arabian Plateau, corresponding to today’s Iraq, mostly, but also parts of modern-day Iran, Syria and Turkey. The 'two rivers' of the name referred to the Tigris and the Euphrates rivers and the land was known as 'Al-Jazirah' (the island) by the Arabs referencing what Egyptologist J.H. Breasted would later call the Fertile Crescent, where Mesopotamian civilization began.

THE CRADLE OF CIVILIZATION

Unlike the more unified civilizations of Egypt or Greece, Mesopotamia was a collection of varied cultures whose only real bonds were their script, their gods, and their attitude toward women.
The social customs, laws, and even language of Akkad, for example, cannot be assumed to correspond to those of Babylon; it does seem, however, that the rights of women, the importance of literacy, and the pantheon of the gods were indeed shared throughout the region (though the gods had different names in various regions and periods). As a result of this, Mesopotamia should be more properly understood as a region that produced multiple empires and civilizations rather than any single civilization. Even so, Mesopotamia is known as the “cradle of civilization” primarily because of two developments that occurred there, in the region of Sumer, in the 4th millenium BCE:

exracted from https://www.ancient.eu/Mesopotamia/